A particle-based microfluidic molecular separation integrating surface-enhanced Raman scattering sensing for purine derivatives analysis
Yi-Ying Wang, Ho-Wen Cheng, Kai-Wei Chang, Jessie Shiue, Juen-Kai Wang, Yuh-Lin Wang & Nien-Tsu Huang October 22, 2021
A particle-based microfluidic molecular separation (PMMS) system was developed which integrates SERS substrate to separate complicate molecule mixture followed by in situ SERS detection. The platform consists of an automatic microfluidic control system to precisely control the sample and reagent flow. The miniaturized PMMS–SERS system enables an easy-to-use and sensitive analyte detection, which could be beneficial in applications requiring bacteria identification and quantification, such as environmental monitoring, AST, and drug development. Image courtesy of the authors.