Sample preparation is a bottleneck for protein, cell and nucleic acid analysis, regardless of the analytical technique used. An important, and tedious, preparation step is selective concentration of the target of interest, particularly when target abundance is low. One approach is insulator-based dielectrophoresis, or iDEP, in which insulators, often etched in glass or stamped in … Read more
Separations of complex peptide mixtures can take too long to elute without the ability to apply a solvent gradient. One solution for applying a gradient is called Microchannel Electrochromatography, or MEC. In reversed phase MEC buffers with aqueous and organic components comprise the mobile phase of a separation through a solid and porous stationary phase … Read more
Many research experiments require the precise control of lasers. The LabSmith LC880 Programmable Experiment Controller handles all aspects of laser timing control, from simple pulsing to sequencing a 2-pulse experiment and beyond. In this application note, we will discuss how to implement a pulsed Nd:YAG laser control system using the LC880. We will expand the … Read more
Many experiments require several processes to coincide with an event of unknown timing. Photographing a projectile in flight, for example, requires accurate coordination of the camera, sensors and flash lamps to capture a projectile of unknown speed. In this study, we examine various ways to control experiments of this nature using the LabSmith LC880 Programmable … Read more
In the “Laser Control with the LC880” application note, we designed a laser control system using the LabSmith LC880 Programmable Logic Controller. In this application note, we’ll discuss two designs for a two-pulse experiment, in which two laser pulses illuminate a fluid to visualize its flow.