Step-by-Step Simple Flow Setup and uProcess Automation

For over a decade, LabSmith has been making microfluidic tools used in top research labs around the world. We now offer these same tools in educational kits available for high-school and undergraduate programs. Our Microfluidics Education Toolkits include an array of reusable microfluidic control components and sensors, interactive software, and curriculum packages to help educators … Read more

Sensirion Flow Sensor Control with uProcess

This application note shows how to use uProcess components and software with a Sensirion flow sensor to develop a continuous-flow system that maintains a constant, set pressure. Download the Application Note here. Download the sample uProcess automation script here.

Degassing a Microfluidic System

Dissolved gas and trapped air bubbles in a microfluidic system can affect repeatability and stability. Degassing a fluid system is easy using a LabSmith Breadboard Reservoir or Chip Reservoir.

A particle-based microfluidic molecular separation integrating surface-enhanced Raman scattering sensing for purine derivatives analysis

A particle-based microfluidic molecular separation (PMMS) system was developed which integrates SERS substrate to separate complicate molecule mixture followed by in situ SERS detection. The platform consists of an automatic microfluidic control system to precisely control the sample and reagent flow. The miniaturized PMMS–SERS system enables an easy-to-use and sensitive analyte detection, which could be … Read more

Localized surface plasmon resonance (LSPR) sensor integrated automated microfluidic system for multiplex inflammatory biomarker detection

A localized surface plasmon resonance (LSPR) sensor enables continuous and dynamic inflammatory biomarker detection, we utilized  to perform label-free molecule sensing. The small LSPR sensing mechanism simplifies optical setup and can be easily integrated with a microfluidic device.  An automated microfluidic control system was developed to control reagent guiding and switching in the immunoassay with … Read more

Clinical translation of microfluidic sensor devices: focus on calibration and analytical robustness

This paper discusses approaches to facilitate the use of microfluidics by non-experts in clinical settings outside of the laboratory. The researchers demonstrate a flexible microfluidic platform that can be coupled to microfluidic biosensors and used in conjunction with clinical microdialysis. The precision and control offered by this set-up enables the use of microfluidics by non-experts … Read more

Zero Dead-Volume Mixing with uProcess and Hummingbird Nano Chips

This application note describes how to set up a zero dead volume mixing process using LabSmith’s uProcess syringe pumps, valves, reservoirs and software, and Hummingbird Nano “X” style or “Y” style helical mixer chips. Download the Application Note here. Download the sample uProcess automation script here.

Microfluidic ChipShop Fluidic Interface Options

This guide shows the CapTite™ microfluidic connections required to interface with various, common types of chips available from Microfluidic ChipShop. The types of chips shown below are available through LabSmith as well as through Microfluidic ChipShop.

How to Make Leak-Free, Zero Dead-Volume Microfluidic Connections

CapTite™ fluid routing components provide leak-free connectivity, even at high pressures, for fluid circuits with 360μm capillary, 1/32″ and 1/16″ tubing. This application note describes how to make reliable, tight connections using LabSmith’s CapTite™ microfluidic connectors. View the related video here.

Microfab-less microfluidic capillary electrophoresis devices

Thiago P. Segato, a Samir A. Bhakta, Matthew T. Gordon, Emanuel Carrilho, Peter A. Willis, Hong Jiaod and Carlos D. Garcia,  Anal. Methods, 2013, 5, 1652 (One of the Top 25 Most Read Analytical Methods Articles of 2013). ABSTRACT Compared to conventional benchtop instruments, microfluidic devices possess advantageous characteristics including great portability potential, reduced analysis … Read more